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Nifedipine is contraindicated throughout pregnancy, as administration in animals was associated with embryotoxic, fetotoxic and teratogenic effects. All of the doses associated with teratogenic, embryotoxic or fetotoxic effects in animals were maternally toxic and several times the recommended maximum dose for humans. There are no adequate and well-controlled studies in pregnant women.
Nifedipine passes into the breast milk. As there is no experience of possible effects on infants, breastfeeding should first be stopped if nifedipine treatment becomes necessary during the breastfeeding period.
